Clinical Logic If an illness or syndrome is widespread and debilitating -  search for a cure. If an answer is unproven but appears logical -  pursue it. If the treatment is benign -  try it. If it doesn't work -  nothing lost. If it does work -  great gain. But it may be a placebo effect -  So what? But the "placebo" may modify an unknown pathologic mechanism -  a discovery. But the smart guys and the critics won't accept it -  who cares? To the doctor: If you try such treatment and it works, your patient will love you. The patient couldn't care less about your unbelieving colleagues because -  he is well!